HOMER3
Reactivity: Human, Rat, Dog, Horse, Cow, Pig, Bat, Monkey
WB, IHC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000
Restrictions
For Research Use only
Format
Liquid
Buffer
0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target
HOMER3
(Homer Homolog 3 (Drosophila) (HOMER3))
Alternative Name
Homer-3
Background
This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization.The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides.Alternative splicing results in multiple transcript variants.