SPR antibody (AA 65-253)

Catalog No. ABIN1886601

This anti-SPR antibody is a Rabbit Polyclonal antibody detecting SPR in WB and IF. Suitable for Human.

Quick Overview for SPR antibody (AA 65-253) (ABIN1886601)

Target: SPR (Sepiapterin Reductase (SPR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPR antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-SPR Antibody

Binding Specificity: AA 65-253

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 65 and 253 of Human SPR

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for SPR

Target: SPR (Sepiapterin Reductase (SPR))

Alternative Name: SPR

Background: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4).Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency.A pseudogene has been identified on chromosome 1.[provided by RefSeq]

Molecular Weight: 28 kDa

Gene ID: 6697

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration