ASL antibody (AA 86-335)

Catalog No. ABIN1886687

The Rabbit Polyclonal anti-ASL antibody has been validated for WB and IHC. It is suitable to detect ASL in samples from Human.

Quick Overview for ASL antibody (AA 86-335) (ABIN1886687)

Target: ASL (Argininosuccinate Lyase (ASL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ASL Antibody

Binding Specificity: AA 86-335

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 86 and 335 of Human ASL

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for ASL

Target: ASL (Argininosuccinate Lyase (ASL))

Alternative Name: Argininosuccinate Lyase

Background: This gene encodes a member of the lyase 1 family.The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle.Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.A nontranscribed pseudogene is also located on the long arm of chromosome 22.Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq]

Molecular Weight: 49 kDa

Gene ID: 435

NCBI Accession: NP_001020117, NM_001024946

Pathways: Response to Growth Hormone Stimulus