STS antibody (AA 182-195)

Catalog No. ABIN1886844

This anti-STS antibody is a Rabbit Polyclonal antibody detecting STS in WB, ELISA and ICC. Suitable for Human.

Quick Overview for STS antibody (AA 182-195) (ABIN1886844)

Target: STS (Steroid Sulfatase (STS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Product Details anti-STS Antibody

Binding Specificity: AA 182-195

Purification: Affinity chromatography purified via peptide column

Immunogen: Synthetic peptide corresponding to amino acids 182 to 195 of human ASC.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for STS

Target: STS (Steroid Sulfatase (STS))

Alternative Name: ASC

Background: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases.CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2.A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1.Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells (3, 4).Overexpression of ASC/TMS1 induced DNA fragmentation.ASC/TMS1 is expressed in a variety of human and mouse tissues.

Molecular Weight: 25 kDa

Pathways: Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation