STS antibody (AA 50-195)

Catalog No. ABIN7091698

Product Details anti-STS Antibody

Target: STS (Steroid Sulfatase (STS))

Binding Specificity: AA 50-195

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse

Purification: Purified by Protein A.

Immunogen: Recombinant human ASC

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IF()

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for STS

Target: STS (Steroid Sulfatase (STS))

Alternative Name: ASC (STS Products)

Synonyms: 9130417A21Rik antibody, Asc antibody, CARD5 antibody, TMS-1 antibody, TNS1 antibody, masc antibody, ARSC antibody, ARSC1 antibody, ASC antibody, ES antibody, SSDD antibody, XLI antibody, PYD and CARD domain containing antibody, steroid sulfatase antibody, Pycard antibody, STS antibody, Sts antibody

Background:

Synonyms: TMS1, Apoptosis associated speck like protein containing a CARD, Apoptosis-associated speck-like protein containing a CARD, ASC_HUMAN, CARD 5, CARD5, Caspase recruitment domain containing protein 5, Caspase recruitment domain protein 5, Caspase recruitment domain-containing protein 5, hASC, MGC10332, PYCARD, TMS-1, PYD and CARD domain containing, PYD and CARD domain containing protein, PYD and CARD domain-containing protein, Target of methylation induced silencing 1, Target of methylation-induced silencing 1, TMS 1.

Background: Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

Gene ID: 29108

UniProt: Q9ULZ3

Pathways: Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation