ANKLE1 antibody (C-Term)

Catalog No. ABIN1887038

The Rabbit Polyclonal anti-ANKLE1 antibody has been validated for WB and ELISA. It is suitable to detect ANKLE1 in samples from Human, Rat and Mouse.

Quick Overview for ANKLE1 antibody (C-Term) (ABIN1887038)

Target: ANKLE1 (Ankyrin Repeat and LEM Domain Containing 1 (ANKLE1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKLE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ANKLE1 Antibody

Binding Specificity: C-Term

Cross-Reactivity (Details): Two isoforms of ANKLE1 are known to exist. ANKLE1 antibody is predicted to not cross-react with ANKLE2

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human ANKLE1.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for ANKLE1

Target: ANKLE1 (Ankyrin Repeat and LEM Domain Containing 1 (ANKLE1))

Alternative Name: ANKLE1

Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network.ANKLE1 (Ankyrin repeat and LEM domain containing 1) is a member of ankyrin repeat and LEM domain containing family.It is a potential single-pass membrane protein that contains ankyrin repeats and a Lem domain.Ankyrin repeats mediate protein-protein interactions and are among the most common structural motifs in known proteins.While the function of this protein is still under investigation, its gene locus has been associated with susceptibility to ovarian and breast cancer.
Synonyms: Ankyrin repeat and LEM domain containing 1, ANKRD41, Ankyrin repeat domain-containing protein 41, LEM3, LEMD6, LEM-domain containing protein 3

NCBI Accession: NP_689576