BANP antibody (Center)
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- Target See all BANP Antibodies
- BANP (Protein BANP (BANP))
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Binding Specificity
- Center
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BANP antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 14 amino acid peptide near the center of human BANP.
- Top Product
- Discover our top product BANP Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Handling Advice
- Avoid freezing and thawing repeatly.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- Target
- BANP (Protein BANP (BANP))
- Alternative Name
- BANP (BANP Products)
- Synonyms
- smar1 antibody, smarbp1 antibody, MGC76079 antibody, MGC89601 antibody, BEND1 antibody, SMAR1 antibody, SMARBP1 antibody, AA408158 antibody, zgc:111954 antibody, BTG3 associated nuclear protein antibody, Btg3 associated nuclear protein antibody, BTG3 associated nuclear protein L homeolog antibody, banp antibody, BANP antibody, Banp antibody, banp.L antibody
- Background
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BANP was initially identified as a binding protein to BTG3 in a yeast two-hybrid screen.BANP acts as a tumor suppressor by stabilizing p53 expression and leading to cell cycle arrest.p53 in turn binds to upstream elements of the BANP promoter, thereby forming a feedback loop.BANP is down-regulated in advanced stages of human breast cancer, and its overexpression in breast cancer cell lines inhibits their ability to metastasize by modulating TGF-beta signaling.Furthermore, BANP can modulate NF-kappaB transactivation and can inhibit tumorigenesis by regulating NF-kappaB target genes.Recent experiments have shown that BANP can also repress HIV-1 LTR mediated transcription by tethering the LTR matrix attachment region to nuclear matrix.
Synonyms: BTG3 associated nuclear protein, BEND1, SMAR1, SMARBP1 - NCBI Accession
- NP_001167014
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