Influenza A Matrix Protein 2 antibody (Influenza A Virus H5N1) (N-Term)

Catalog No. ABIN1887830

The Rabbit Polyclonal anti- antibody has been validated for ELISA and WB. It is suitable to detect in samples from Influenza A Virus H5N1.

Quick Overview for Influenza A Matrix Protein 2 antibody (Influenza A Virus H5N1) (N-Term) (ABIN1887830)

Target: Influenza A Matrix Protein 2 (M2)

Reactivity: Influenza A Virus H5N1

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: 13 amino acid peptide from amino terminus of H5N1 M2.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details

Target: Influenza A Matrix Protein 2 (M2)

Target Type: Influenza Protein

Background: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA.Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics.Influenza A can exist in a variety of animals, however, it is in birds that all subtypes can be found.These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes.During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong.The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in Southeast Asia.There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low.The influenza membrane ion channel (M2) is a small transmembrane protein that regulates the pH inside the virion during viral entry into the cell and protects the newly synthesized hemagglutinin during their transport through low pH cellular compartments.It has been suggested as a target of neutralizing antibodies.
Synonyms: Avian Influenza A M2, H5N1 M2, H5N1 membrane ion channel 2