ICOS antibody (C-Term)

Catalog No. ABIN1904299

This Rabbit Monoclonal antibody specifically detects ICOS in IHC and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ICOS antibody (C-Term) (ABIN1904299)

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ICOS antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: SP98

Product Details anti-ICOS Antibody

Binding Specificity: C-Term

Specificity: Human ICOS

Purification: Protein A/G purified

Immunogen: Synthetic peptide corresponding to C-terminus of human CD278.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (1:100)

Usage: IMMUNOHISTOCHEMISTRY: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. Antibody Dilution: If using the concentrate format of this product, dilute the antibody 1:100. Antigen Retrieval: Boil tissue section in 1  mM EDTA buffer,  pH 8.0 for 10 min followed by cooling at room temperature for 20 min. Primary Antibody Incubation: Incubate for 30 minutes at room temperature. Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05 % Tween. Positive control: Tonsil, reactive lymph node . Cellular localization: Membrane.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.6, 1 % BSA, 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for ICOS

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Alternative Name: ICOS / CD278

Background: Name/Gene ID: ICOS

Synonyms: ICOS, AILIM, CD278, CVID1, Inducible costimulator, Inducible T-cell co-stimulator, CD278 antigen, Inducible T-cell costimulator

Gene ID: 29851

Pathways: Cancer Immune Checkpoints