HSC70 antibody

Catalog No. ABIN190694

The Rabbit Polyclonal anti-HSC70 antibody has been validated for WB and IP. It is suitable to detect HSC70 in samples from Fish and Mammalian. There is 1 publication available.

Quick Overview for HSC70 antibody (ABIN190694)

Target: HSC70 (Heat Shock Cognate 70 (HSC70))

Reactivity: Fish, Mammalian

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSC70 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-HSC70 Antibody

Specificity: Predicted reactivity: vertebrates including bovine, hen, mouse, rat, insects including Drosophilamelanogaster.

Purification: Affinity purified

Immunogen: KLH-conjugated synthetic peptide conserved across all known sequences ofHSP70 P08107 and HSC70 proteins P11142

Application Details

Application Notes: Recommended Dilution 1: 1000 with standard ECL (WB), 1: 10 000 with ECL Advance (GE Healthcare),1: 1000 (IP).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: affinity purified rabbit serum on peptide column, in PBS pH 7.4

Storage: -20 °C

Storage Comment: store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

References for anti-HSC70 antibody (ABIN190694)

Gorovits, Moshe, Ghanim, Czosnek: "Recruitment of the host plant heat shock protein 70 by Tomato yellow leaf curl virus coat protein is required for virus infection." in: PLoS ONE, Vol. 8, Issue 7, pp. e70280, (2013) (PubMed).

Target Details for HSC70

Target: HSC70 (Heat Shock Cognate 70 (HSC70))

Alternative Name: Heat shock protein 70/Heat shock cognate protein 70 (HSP70/HSC70)

Background: Heat shock protein 70 (Hsp70) is the major stress-inducible protein invertebrates and is highly conserved throughout evolution. It plays a role as amolecular chaperone and is important for allowing cells to cope with acute stressor insult, especially those affecting the protein machinery. Heat shock cognateprotein 70 (HSC70) is a highly conserved protein and a member of the family ofmolecular chaperones. Alternative names: HSP70.1, HSP70-1/HSP70-2, Heatshock 70 kDa protein 8