HSC70 antibody

Catalog No. ABIN190694

There is 1 publication for this product available. The Rabbit Polyclonal anti-HSC70 antibody is suitable to detect HSC70 in samples from Arenicella xantha, Dogfish (Squalus), Fish, Fungus (Antrodia), Fungus (Gloeophyllum), Fungus (Junghuhnia), Fungus (Phlebia), Fungus (Postia), Mammalian and Ray (Raja). It has been validated for WB and IP.

Quick Overview for HSC70 antibody (ABIN190694)

Target: HSC70 (Heat Shock Cognate 70 (HSC70))

Reactivity: Arenicella xantha, Dogfish (Squalus), Fish, Fungus (Antrodia), Fungus (Gloeophyllum), Fungus (Junghuhnia), Fungus (Phlebia), Fungus (Postia), Mammalian, Ray (Raja)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSC70 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-HSC70 Antibody

Purpose: Anti-HSP70/HSC70 | Heat shock protein 70/Heat shock cognate protein 70, Affinity purified

Specificity: Predicted reactivity: vertebrates including bovine, hen, mouse, rat, insects including Drosophilamelanogaster.

Cross-Reactivity (Details): Fish, mammals, fungi: Antrodia infirma, A. sinuosa, A. xantha, Gloeophyllum protractum, Gloeophyllum sepiarium, G. carbonarium, Junghunia luteoalba, Mustelus canis, Oligoporus sericiomollis, Phlebia cornea, Squalus acanthias, Zearaja maugeana
Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Predicted Reactivity: Bovine,Danio rerio (Zebrafish),Drosophila melanogaster,Hen,Mouse,Rat

Purification: Immunogen affinity purified serum

Immunogen: KLH-conjugated synthetic peptide conserved across all known sequences of HSP70 P08107 and HSC70 proteins P11142

Application Details

Application Notes: 1 : 1000 (IP), 1 : 1000-1: 5000 (WB)

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μL of sterile water

Buffer: Immunogen affinity purified serum in PBS pH 7.4.

Handling Advice: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

Storage: -20 °C

Storage Comment: Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

References for anti-HSC70 antibody (ABIN190694)

Gorovits, Moshe, Ghanim, Czosnek: "Recruitment of the host plant heat shock protein 70 by Tomato yellow leaf curl virus coat protein is required for virus infection." in: PLoS ONE, Vol. 8, Issue 7, pp. e70280, (2013) (PubMed).

Target Details for HSC70

Target: HSC70 (Heat Shock Cognate 70 (HSC70))

Alternative Name: Heat shock protein 70/Heat shock cognate protein 70 (HSP70/HSC70)

Background:

Background: Heat shock protein 70 (Hsp70) is the major stress-inducible protein in vertebrates and is highly conserved throughout evolution. It plays a role as a molecular chaperone and is important for allowing cells to cope with acute stress or insult, especially those affecting the protein machinery. Heat shock cognate protein 70 (HSC70) is a highly conserved protein and a member of the family of molecular chaperones. Alternative names: HSP70.1, HSP70-1/HSP70-2, Heat shock 70 kDa protein 8

Additional information: For detection of plant and algal cytoplasmic hsp70 we recommend following product: AS08 371

Molecular Weight: 70 kDa

Gene ID: 3303

UniProt: P08107, P11142