PRNP antibody

Catalog No. ABIN1926897

The Rabbit Polyclonal anti-PRNP antibody (Clone T16-R) (ABIN1926897) specifically detects PRNP in WB, IHC, ELISA, IP and IHC (p). The antibody is reactive with Human, Mouse, Rat, Cow and Sheep samples.

Quick Overview for PRNP antibody (ABIN1926897)

Target: PRNP (Prion Protein (PRNP))

Reactivity: Human, Mouse, Rat, Cow, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRNP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: T16-R

Product Details anti-PRNP Antibody

Specificity: Antibody recognizes both forms of prion protein - PrPC and PrPSC, untreated with proteinase-K.

Purification: Affinity purified

Immunogen: Peptide derived from N-terminal peptide of human prion protein, just before the first octapeptide sequnce repeat

Application Details

Application Notes: Approved: ELISA (1:10000 - 1:20000), IHC, IHC-P (1:100), IP, WB (1:1000)

Usage: For immunohistochemistry on paraffin embedded tissues, a citrate buffer,  pH 6.0 is suggeted for antigen retrieval.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 20 mM Tris-HCl,  pH 8.0, 10 mg/mL BSA stabilzer, 0.05 % sodium azide preservative

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C. Avoid freeze-thaw cycles.

Target Details for PRNP

Target: PRNP (Prion Protein (PRNP))

Alternative Name: PRNP / PrP / Prion

Background: Name/Gene ID: PRNP

Synonyms: PRNP, AltPrP, ASCR, CD230 antigen, CJD, KURU, Major prion protein, p27-30, Prion, Prion-related protein, PRIP, Prion protein (p27-30), PrP, PrP33-35C, BSE, CD230, Prion protein, PrP27-30, PrPc

Gene ID: 5621

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation