HLA-B antibody (N-Term)

Catalog No. ABIN1944779

Product Details anti-HLA-B Antibody

Target: HLA-B (Major Histocompatibility Complex, Class I, B (HLA-B))

Binding Specificity: AA 75-107, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HLA-B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HLA-B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 75-107 amino acids from the N-terminal region of human HLA-B.

Clone: RB47637

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-HLA-B antibody (ABIN1944779)

Lin, Tokunaga, Tanaka, Nakajima, Imanishi, Kashiwase, Bannai, Mizuno, Akaza, Tadokoro, Shibata, Juji: "Further molecular diversity in the HLA-B15 group." in: Tissue antigens, Vol. 47, Issue 4, pp. 265-74, (1996) (PubMed).

Hildebrand, Domena, Shen, Lau, Terasaki, Bunce, Marsh, Guttridge, Bias, Parham: "HLA-B15: a widespread and diverse family of HLA-B alleles." in: Tissue antigens, Vol. 43, Issue 4, pp. 209-18, (1994) (PubMed).

Little, Parham: "The HLA-Bw75 subtype of B15: molecular characterization and comparison with crossreacting antigens." in: Tissue antigens, Vol. 38, Issue 4, pp. 186-90, (1992) (PubMed).

Madrigal, Belich, Hildebrand, Benjamin, Little, Zemmour, Ennis, Ward, Petzl-Erler, du Toit: "Distinctive HLA-A,B antigens of black populations formed by interallelic conversion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 149, Issue 10, pp. 3411-5, (1992) (PubMed).

Watkins, McAdam, Liu, Strang, Milford, Levine, Garber, Dogon, Lord, Ghim: "New recombinant HLA-B alleles in a tribe of South American Amerindians indicate rapid evolution of MHC class I loci." in: Nature, Vol. 357, Issue 6376, pp. 329-33, (1992) (PubMed).

Target Details for HLA-B

Target: HLA-B (Major Histocompatibility Complex, Class I, B (HLA-B))

Alternative Name: HLA-B (HLA-B Products)

Background: Involved in the presentation of foreign antigens to the immune system.

UniProt: P30464

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response