MYB antibody (AA 1-185)

Catalog No. ABIN1944794

The Mouse Monoclonal anti-MYB antibody has been validated for WB. It is suitable to detect MYB in samples from Human. There are 3+ publications available.

Quick Overview for MYB antibody (AA 1-185) (ABIN1944794)

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MYB antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 1279CT309-289

Product Details anti-MYB Antibody

Binding Specificity: AA 1-185

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This MYB antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 1-185 amino acids from the Central region of human MYB.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-MYB antibody (ABIN1944794)

Close, Game, Clark, Bergounioux, Gerovassili, Thein: "Genome annotation of a 1.5 Mb region of human chromosome 6q23 encompassing a quantitative trait locus for fetal hemoglobin expression in adults." in: BMC genomics, Vol. 5, Issue 1, pp. 33, (2004) (PubMed).

Westin, Gorse, Clarke: "Alternative splicing of the human c-myb gene." in: Oncogene, Vol. 5, Issue 8, pp. 1117-24, (1990) (PubMed).

Majello, Kenyon, Dalla-Favera: "Human c-myb protooncogene: nucleotide sequence of cDNA and organization of the genomic locus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 24, pp. 9636-40, (1987) (PubMed).

Target Details for MYB

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Alternative Name: MYB

Background: Transcriptional activator, DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

Molecular Weight: 72341

Gene ID: 4602

UniProt: P10242

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process