PDE11A antibody (Internal Region)

Catalog No. ABIN195735

The Goat Polyclonal anti-PDE11A antibody (ABIN195735) specifically detects PDE11A in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for PDE11A antibody (Internal Region) (ABIN195735)

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This PDE11A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Grade: Verified

Product Details anti-PDE11A Antibody

Binding Specificity: Internal Region

Purpose: PDE11A

Sequence: NSFKESMEKS SYSD

Specificity: This antibody is expected to recognise all four reported isoforms (NP_058649.3 , NP_001070665.1, NP_001070826.1, NP_001070664.1).

Cross-Reactivity: Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-NSFKESMEKSSYSD, from the internal region of the protein sequence according to NP_058649.3 , NP_001070665.1, NP_001070826.1, NP_001070664.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Prostate. Recommended concentration: 10 μg/mL.

Western Blot: Approx 60-65 kDa band observed in Human Skeletal Muscle and Human Prostate lysates (calculated MW of 65.7 kDa according to NP_001070826.1). Recommended concentration: 0.5-1.5 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for PDE11A

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Alternative Name: PDE11A

Background: PDE11A, phosphodiesterase 11A , FLJ23693, MGC133355, MGC133356, PPNAD2 , cAMP and cGMP cyclic nucleotide phosphodiesterase 11A, cyclic nucleotide phosphodiesterase 11A, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

Gene ID: 50940, 241489, 140928

NCBI Accession: NP_058649, NP_001070665, NP_001070826, NP_001070664

Pathways: cAMP Metabolic Process