CD16 antibody

Catalog No. ABIN1959958

This Mouse Monoclonal antibody specifically detects CD16 in FACS, IP, Func, IHC, IHC (fro), BR, Neut, Dep and Inhibition. It exhibits reactivity toward Human and Primate.

Quick Overview for CD16 antibody (ABIN1959958)

Target: CD16

Reactivity: Human, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD16 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Neutralization (Neut), Depletion (Dep), Blocking Antibody (Inhibition)

Clone: 3G8

Product Details anti-CD16 Antibody

Specificity: Monoclonal antibody 3G8 recognizes CD16, a low affinity receptor for aggregated IgG (FcgammaRIII antigen). CD16 exists in two different isoforms: CD16a (FcgammaRIIIA, 50-65 kD, expressed on NK-cells, monocytes and macrophages) and CD16b (FcgammaRIIIB, 48 kD, mainly expressed on neutrophils).

Purification: Protein A purified

Immunogen: Human neutrophils.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Block, Depl, Flo, Func, IHC, IHC-Fr, Inhb, IP, Neut

Usage: Flow Cytometry: Recommended dilution - 6 μg/mL. Immunohistochemistry (frozen sections): Application note - acetone fixation. Functional Application: In vitro Stimulation of NK cell proliferation, blocking of IgG binding and phagocytosis, inhibition of cyt

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 15 mM sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for CD16

Target: CD16

Alternative Name: CD16

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process