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Integrin beta 3 antibody (AA 771-775)

ITGB3 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN197246
  • Target See all Integrin beta 3 (ITGB3) Antibodies
    Integrin beta 3 (ITGB3)
    Binding Specificity
    • 26
    • 16
    • 15
    • 13
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 771-775
    Reactivity
    • 181
    • 93
    • 60
    • 16
    • 15
    • 13
    • 13
    • 10
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 120
    • 63
    • 11
    • 2
    Rabbit
    Clonality
    • 115
    • 79
    Polyclonal
    Conjugate
    • 104
    • 15
    • 11
    • 10
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 3 antibody is un-conjugated
    Application
    • 123
    • 84
    • 52
    • 47
    • 28
    • 27
    • 23
    • 19
    • 15
    • 13
    • 13
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Affinity-chromatography using epitope-specific immunogen
    Immunogen
    Synthesized non-phosphopeptide derived from Human Integrin beta-3 around amino acids 771~775
    Top Product
    Discover our top product ITGB3 Primary Antibody
  • Application Notes
    Immunohistochemistry (1/50approx. 1/100). Western Blot (1/500-1/1,000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    Integrin beta 3 (ITGB3)
    Alternative Name
    CD61 / ITGB3 (ITGB3 Products)
    Background
    Human Integrin beta 3 (CD61) antigen is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells. The integrin beta 3 chain of the vitronectin receptor and GPIIb/IIIa complex. The beta 3 integrin chain is a 90-110 kDa glycoprotein polypeptide which is expressed on platelets, megakaryocytes, macrophages, osteoclasts and synovial lining cells.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
    Gene ID
    9606
    UniProt
    P05106
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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