BCR antibody (AA 1221-1271)

Catalog No. ABIN1977889

This Rabbit Polyclonal antibody specifically detects BCR in WB, IF, FACS, ICC, IP and PLA. It exhibits reactivity toward Human, Mouse, Rat, Chicken, Dog, Xenopus laevis and Zebrafish (Danio rerio).

Quick Overview for BCR antibody (AA 1221-1271) (ABIN1977889)

Target: BCR (Breakpoint Cluster Region (BCR))

Reactivity: Human, Mouse, Rat, Chicken, Dog, Xenopus laevis, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCR antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP), Proximity Ligation Assay (PLA)

Product Details anti-BCR Antibody

Binding Specificity: AA 1221-1271

Specificity: Region between residue 1221 and 1271 of human breakpoint cluster region using the numbering given in entry NP_004318.3 (GeneID 613).

Purification: Immunoaffinity purified

Isotype: IgG

Application Details

Application Notes: Approved: Flo, ICC (1:500 - 1:2000), IF (1:500 - 1:2000), IP (10 μg/mg lysate), PLA (1:1000 - 1:20000), WB (1:2000 - 1:10000)

Usage: Immunocytochemistry: Epitope retrieval with citrate buffer  pH 6.0 is recommended for FFPE cells. For cytospin preparations of formaldehyde fixed cells permeabilization with Triton-X 100 is recommended.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-citrate/phosphate buffer,  pH 7-8, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for BCR

Target: BCR (Breakpoint Cluster Region (BCR))

Alternative Name: CML / BCR

Background: Name/Gene ID: BCR
Subfamily: BCR
Family: Protein Kinase

Synonyms: BCR, Acute lymphocytic leukemia, ALL, BCR1, BCR/FGFR1 chimera protein, Breakpoint cluster region, Chronic myeloid leukemia, D22S11, CML, D22S662, Philadelphia chromosome, PHL, FGFR1/BCR chimera protein

Gene ID: 613

Pathways: Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling