ITGA6 antibody

Catalog No. ABIN198797

The Mouse Monoclonal anti-ITGA6 antibody is suitable to detect ITGA6 in samples from Human and Mouse. It has been validated for FACS, IHC, IP, IHC (fro) and Func.

Quick Overview for ITGA6 antibody (ABIN198797)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA6 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Product Details anti-ITGA6 Antibody

Specificity: Recognizes human Cdw49f-antigen, 120kD, (GP Ic or VLA-6 alpha-chain). Inhibits platelet adhesion to laminin. Reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukemia cells (alpha-6 beta-1). Reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. Species cross-reactivity: Mouse, Cynomolgus monkey, porcine, and canine.

Purification: Protein G purified

Immunogen: BALB/c mouse mammary tumor cells.

Type of Immunogen: Cells

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (1:25 - 1:50), Func, IHC, IHC-Fr, IP

Usage: Suitable for use in Flow Cytometry, Immunohistochemistry, Immunoprecipitation and Inhibition. Flow Cytometry: 1:25-1:50, Use 10 μL per 1 x10⁶ in 100 μL. Immunohistochemistry: Frozen tissue sections. Inhibition of laminin binding: 40 μg/mL. Positive control: Human tonsil (for Immunohistochemistry).

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: ITGA6/Integrin Alpha 6/CD49f

Background: Name/Gene ID: ITGA6
Family: Integrin

Synonyms: ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B

Gene ID: 3655

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex