Rabies Virus Nucleoprotein (RABV N) antibody

Catalog No. ABIN1993849

This Rabbit Polyclonal antibody specifically detects Rabies Virus Nucleoprotein in ELISA and WB. It exhibits reactivity toward Rabies Virus.

Quick Overview for Rabies Virus Nucleoprotein (RABV N) antibody (ABIN1993849)

Target: Rabies Virus Nucleoprotein (RABV N)

Reactivity: Rabies Virus

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details

Purification: Caprylic Acid Ammonium Sulfate Precipitation

Immunogen: Recombinant Rabies virus Nucleoprotein protein

Isotype: IgG

Application Details

Application Notes: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.

Storage: -20 °C/-80 °C

Storage Comment: Upon delivery aliquot and store at -20 °C or -80 °C.

Target Details

Target: Rabies Virus Nucleoprotein (RABV N)

Alternative Name: Rabies Virus Nucleoprotein

Target Type: Influenza Protein

Background: Encapsidates the genome in a ratio of one protein N per nine ribonucleotides, protecting it from nucleases. If expressed without protein P it binds non-specifically RNA and therefore can bind it\'s own mRNA. Interaction with protein P abolishes any non-specific RNA binding, and prevents phosphorylation. The soluble N-P complex encapsidates specifically the genomic RNA, with protein N protecting the genome like a pearl necklace. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for viral transcription and replication. Protein N binds protein P in the NC through a different interaction, and can be phosphorylated. Subsequent viral replication is dependent on intracellular concentration of newly synthesized protein N. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases
Synonyms: NP, Nucleocapsid protein, Protein N, N

UniProt: P15197