UBE2V2 antibody (AA 2-145) (FITC)

Catalog No. ABIN1994540

The Rabbit Polyclonal anti-UBE2V2 antibody has been validated for WB and ELISA. It is suitable to detect UBE2V2 in samples from Human.

Quick Overview for UBE2V2 antibody (AA 2-145) (FITC) (ABIN1994540)

Target: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2V2 antibody is conjugated to FITC

Application: Western Blotting (WB), ELISA

Product Details anti-UBE2V2 Antibody (FITC)

Binding Specificity: AA 2-145

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin-conjugating enzyme E2 variant 2 protein (2-145AA)

Isotype: IgG

Application Details

Application Notes: Optimal working concentration should be determinde by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for UBE2V2

Target: UBE2V2 (Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2))

Alternative Name: UBE2V2

Background:

Background: Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through \'Lys-63\'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

Aliases: 1 alpha 25 dihydroxyvitamin D3 inducible antibody, DDVit 1 antibody, DDVIT1 antibody, EDAF-1 antibody, EDAF1 antibody, EDPF-1 antibody, EDPF1 antibody, Enterocyte differentiation associated factor EDAF 1 antibody, Enterocyte differentiation promoting factor antibody, Enterocyte differentiation-associated factor 1 antibody, Enterocyte differentiation-promoting factor 1 antibody, Methyl methanesulfonate sensitive 2 antibody, MMS 2 antibody, MMS2 antibody, MMS2 homolog antibody, UB2V2_HUMAN antibody, UBE2V 2 antibody, UBE2V2 antibody, Ubiquitin conjugating enzyme E2 variant 2 antibody, Ubiquitin conjugating enzyme E2v2 antibody, Ubiquitin-conjugating enzyme E2 variant 2 antibody, UEV 2 antibody, UEV2 antibody, Vitamin D3 inducible protein antibody, Vitamin D3-inducible protein antibody

UniProt: Q15819

Pathways: Positive Regulation of Response to DNA Damage Stimulus