CYLD antibody (AA 32-45)

Catalog No. ABIN200017

This Rabbit Polyclonal antibody specifically detects CYLD in WB and ICC. It exhibits reactivity toward Human, Mouse, Hamster, Chicken, Cow, Dog, Guinea Pig, Horse, Monkey and Rabbit.

Quick Overview for CYLD antibody (AA 32-45) (ABIN200017)

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Reactivity: Human, Mouse, Hamster, Chicken, Cow, Dog, Guinea Pig, Horse, Monkey, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYLD antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-CYLD Antibody

Binding Specificity: AA 32-45

Specificity: The amino acid sequence used has 100 % identity in human, mouse, chimpanzee, bovine and feline, and 92 % homologous in rat. Human CYLD is a 956 amino acid protein and the approximate theoretical size is 105 kD.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Dog, Bovine, Hamster, Panda, Horse, Rabbit, Guinea pig, Turkey, Zebra finch, Chicken (100%) Rat, Elephant, Platypus (93%) Opossum (86%).

Purification: Protein G purified

Immunogen: A synthetic peptide (DKQTQKLLKVPKGS) corresponding to amino acids 32-45 of human CYLD, GenBank no. ref|NP_001035814.1|. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Dog, Bovine, Hamster, Panda, Horse, Rabbit, Guinea pig, Turkey, Zebra finch, Chicken (100%), Rat, Elephant, Platypus (93%), Opossum (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: ICC (5 μg/mL), WB (2 - 4 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CYLD

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Alternative Name: CYLD

Background: Name/Gene ID: CYLD

Synonyms: CYLD, CDMT, Deubiquitinating enzyme CYLD, CYLDI, EAC, HSPC057, MFT1, MFT, SBS, TEM, BRSS, Ubiquitin thiolesterase CYLD, USPL2, CYLD1, KIAA0849, Ubiquitin thioesterase CYLD

Gene ID: 1540

NCBI Accession: NP_001035814

UniProt: Q9NQC7

Pathways: Apoptosis, Activation of Innate immune Response