CD28 antibody

Catalog No. ABIN200481

This anti-CD28 antibody is a Mouse Monoclonal antibody detecting CD28 in FACS and Func. Suitable for Human.

Quick Overview for CD28 antibody (ABIN200481)

Target: CD28

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD28 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Product Details anti-CD28 Antibody

Specificity: Recognizes the 44kD antigen found on a sub-population of T-cells and activated B cells. These CD28+ CD8 cells are now known to be cytotoxic T-cell precursors. Does not react with B cells, granulocytes or monocytes. Species cross-reactivity: No cross-reactivity with canine tissues.

Purification: Ion exchange chromatography

Immunogen: Human T lymphocytes.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func

Usage: Suitable for use in Flow Cytometry, T cell proliferation and in cell stimulation studies where it has been suggested that measuring T cell function in HIV infected asymptomatic patients may be an early indicator of AIDS, independent of CD4+ cell counts.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 20 mM Tris,  pH 8.0, 150 mM sodium chloride

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD28

Target: CD28

Alternative Name: CD28

Background: Name/Gene ID: CD28

Synonyms: CD28, CD28 antigen, CD28 antigen (Tp44), Tp44, CD28 Molecule

Gene ID: 940

UniProt: P10747

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response