ITGA6 antibody

Catalog No. ABIN200573

The Mouse Monoclonal anti-ITGA6 antibody has been validated for FACS, IHC, IP and IHC (fro). It is suitable to detect ITGA6 in samples from Human.

Quick Overview for ITGA6 antibody (ABIN200573)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA6 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ITGA6 Antibody

Specificity: Specific to the integrin alpha-6 chain which is expressed on epithelial and endothelial basement membrane. The VLA alpha-6 chain, which consists of a single disulphide linked 120kD subunit and a small doublet subunit of 25/30kD, is non covalently associated with the VLA beta-chain (CD29) in VLA-6 or alpha 6/beta 1 complex or with integrin beta 4 chain (alpha 6/beta 4). The antigen is also expressed on platelets, monocytes, thymocytes and T lymphocytes.

Purification: Protein A purified

Immunogen: Cell line SW/222 (Human colorectal carcinoma).

Isotype: IgG2b

Application Details

Application Notes: Approved: Flo, IHC, IHC-Fr, IP

Usage: Immunohistological studies on frozen sections. Immunoprecipitation of the laminin receptor. Flow Cytometry.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 10 mM sodium azide, 1 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: ITGA6/Integrin Alpha 6/CD49f

Background: Name/Gene ID: ITGA6
Family: Integrin

Synonyms: ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B

Gene ID: 3655

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex