CMA1 antibody (Biotin)

Catalog No. ABIN201287

The Mouse Monoclonal anti-CMA1 antibody has been validated for IHC and ICC. It is suitable to detect CMA1 in samples from Human.

Quick Overview for CMA1 antibody (Biotin) (ABIN201287)

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CMA1 antibody is conjugated to Biotin

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: B7

Product Details anti-CMA1 Antibody (Biotin)

Specificity: Recognizes human mast cell chymase.

Purification: Ion exchange chromatography

Immunogen: Chymase purified from human skin.

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ICC (0.5 - 1 μg/mL), IHC (0.5 - 1 μg/mL)

Usage: Suitable for use in Immunohistochemistry and Immunocytochemistry. Not recommended for Western Blot. Immunohistochemistry/Immunocytochemistry: 0.5-1 μg/mL, For optimal results, tissues or cytospin preparations should be fixed in Carnoy's Fluid (60 % ethanol, 30 % chloroform, 10 % glacial acetic acid). Not recommended for use on formaldehyde fixed tissue. Positive control: Lung, Heart, Skin, Placenta. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Not recommended for: WB

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.1, 0.09 % sodium azide, 15 mg/mL BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.

Target Details for CMA1

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Alternative Name: CMA1 / MCT1 / Chymase

Background: Name/Gene ID: CMA1
Subfamily: Serine S1
Family: Protease

Synonyms: CMA1, Chymase, Chymase, heart, Chymase, mast cell, CYH, Mast cell chymase, Mcpt5, MCT1, Mast cell protease 5, Mast cell protease I, Heart chymase, Alpha-chymase, Chymase 1, Chymase 1, mast cell, CYM

Gene ID: 1215

UniProt: P23946

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis