MAP3K8 antibody (AA 396-445)

Catalog No. ABIN202595

The Rabbit Polyclonal anti-MAP3K8 antibody has been validated for WB. It is suitable to detect MAP3K8 in samples from Human, Rat, Cow, Monkey, Horse, Dog, Rabbit, Bat and Hamster.

Quick Overview for MAP3K8 antibody (AA 396-445) (ABIN202595)

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Reactivity: Human, Rat, Cow, Monkey, Horse, Dog, Rabbit, Bat, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP3K8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MAP3K8 Antibody

Binding Specificity: AA 396-445

Specificity: Human MAP3K8

Predicted Reactivity: Percent identity by BLAST analysis: Human, Rat, Dog, Bovine, Horse (100%) Mouse (92%) Chicken (84%).

Purification: Protein A purified

Immunogen: Synthetic peptide located between aa396-445 of human MAP3K8 (P41279, NP_005195). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Galago, Marmoset, Rat, Dog, Bovine, Bat, Hamster, Elephant, Panda, Horse, Platypus (100%), Mouse, Guinea pig, Xenopus (92%), Lizard (91%), Opossum, Turkey, Chicken (84%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (2.5 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for MAP3K8

Target: MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

Alternative Name: MAP3K8 / TPL2

Background: Name/Gene ID: MAP3K8
Subfamily: MAP3K
Family: Protein Kinase

Synonyms: MAP3K8, C-COT, Cancer Osaka thyroid oncogene, COT, Ewing sarcoma transformant, EST, MEKK8, Proto-oncogene c-Cot, TPL2, Tumor progression locus 2, Protein kinase cot, Tpl-2, ESTF

Gene ID: 1326

NCBI Accession: NP_005195

UniProt: P41279

Pathways: PI3K-Akt Signaling, TCR Signaling