SMAD1 antibody (pSer463, Ser465)

Catalog No. ABIN204727

This Rabbit Polyclonal antibody specifically detects SMAD1 in WB. It exhibits reactivity toward Human, Mouse and Pig.

Quick Overview for SMAD1 antibody (pSer463, Ser465) (ABIN204727)

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Reactivity: Human, Mouse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMAD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SMAD1 Antibody

Binding Specificity: pSer463, Ser465

Specificity: Reacts with the human, mouse and pig Smad1 proteins. On Western blots, it identifies a single band at ~52kD. A ~140kD band of unknown origin is seen in SK-OV-3 cell lysates and a ~200kD band of unknown origin is seen in NIH3T3 cell lysates. Reactivity has been confirmed with human HepG2 and SK-OV-3, African Green monkey COS-7, and mouse NIH3T3 cell lysates, as well as with fetal mouse muscle and thymus homogenates.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide derived from an internal region of the human Smad1 protein.

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (1 - 3 μg/mL)

Usage: Suitable for use in Western Blot. Western Blot: 1-3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for SMAD1

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Alternative Name: SMAD1

Background: Name/Gene ID: SMAD1

Synonyms: SMAD1, BSP1, BSP-1, JV4-1, MADH1, Mothers against DPP homolog 1, JV41, SMAD family member 1, TGF-beta signaling protein 1, MADR1, HSMAD1, MAD homolog 1, Mad-related protein 1, SMAD 1

Gene ID: 4086

UniProt: Q15797

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development