SMAD1 antibody (AA 20-330)

Catalog No. ABIN6242630

This Mouse Monoclonal antibody specifically detects SMAD1 in WB, IF and IHC (p). It exhibits reactivity toward Human.

Quick Overview for SMAD1 antibody (AA 20-330) (ABIN6242630)

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SMAD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1356CT119-18-55

Product Details anti-SMAD1 Antibody

Binding Specificity: AA 20-330

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This SMAD1 antibody is generated from a mouse immunized with a recombinant protein between 20-330 amino acids from human SMAD1.

Isotype: IgG1 kappa

Application Details

Application Notes: IF: 1:25. WB: 1:2000. IHC-P: 1:25. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for SMAD1

Target: SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

Alternative Name: SMAD1

Background: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

Molecular Weight: 52260

UniProt: Q15797

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development