FAS antibody (Extracellular Domain) (FITC)

Catalog No. ABIN7472936

The Mouse Monoclonal anti-FAS antibody has been validated for FACS. It is suitable to detect FAS in samples from Human and Rhesus Monkey.

Quick Overview for FAS antibody (Extracellular Domain) (FITC) (ABIN7472936)

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Reactivity: Human, Rhesus Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This FAS antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Product Details anti-FAS Antibody (FITC)

Binding Specificity: Extracellular Domain

Specificity: 3/17 recognizes the human CD95 cell surface antigen, a 40-50kD glycoprotein expressed by activated T and B cells, NK cells and thymocytes.

Purification: Protein A purified

Immunogen: Fusion protein comprising extracellular domain of human Fas linked to human Fc.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1 - 1:10)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for FAS

Target: FAS (TNF Receptor Superfamily, Member 6 (FAS))

Alternative Name: CD95 / FAS

Background: Name/Gene ID: FAS
Family: TNF Receptor

Synonyms: FAS, ALPS1A, APO-1, APT1, Apo-1 antigen, APO-1 cell surface antigen, Apo11 antigen, Apoptosis antigen 1, CD95 antigen, Delta Fas/APO-1/CD95, Fas AMA, FAS1, Fasl receptors, FASLG receptor, FASTM, FAS 827dupA, Fasl receptor, TNFRSF6, CD95

Gene ID: 355

UniProt: P25445

Pathways: p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity