C5AR1 antibody (Biotin)
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- Target See all C5AR1 Antibodies
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This C5AR1 antibody is conjugated to Biotin
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Application
- Flow Cytometry (FACS)
- Specificity
- Recognizes murine CD88, a 45kD G-protein coupled cell surface receptor, which is otherwise known as C5aR. The CD88 Molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes. Clone 10/92 does not block the binding of the C5a to murine CD88.
- Purification
- Protein G purified
- Immunogen
- RBL-2H3 transfected cells expressing murine C5aR.
- Isotype
- IgG2a
- Top Product
- Discover our top product C5AR1 Primary Antibody
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- Application Notes
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Approved: Flo (1:1)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Comment
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Target Species of Antibody: Mouse
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C,-20 °C
- Storage Comment
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- Alternative Name
- C5AR1 / CD88 / C5a Receptor (C5AR1 Products)
- Background
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Name/Gene ID: C5AR1
Subfamily: Anaphylatoxin
Family: GPCR
Synonyms: C5AR1, C5A, C5a-R, C5a ligand, C5a receptor, CD88, C5a anaphylatoxin receptor, C5AR, C5R1, CD88 antigen - Gene ID
- 728
- UniProt
- P21730
- Pathways
- Complement System
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