C5AR1 antibody (Biotin)

Catalog No. ABIN206604

This anti-C5AR1 antibody is a Rat Monoclonal antibody detecting C5AR1 in FACS. Suitable for Mouse.

Quick Overview for C5AR1 antibody (Biotin) (ABIN206604)

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This C5AR1 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Product Details anti-C5AR1 Antibody (Biotin)

Specificity: Recognizes murine CD88, a 45kD G-protein coupled cell surface receptor, which is otherwise known as C5aR. The CD88 Molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes. Clone 10/92 does not block the binding of the C5a to murine CD88.

Purification: Protein G purified

Immunogen: RBL-2H3 transfected cells expressing murine C5aR.

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (1:1)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Alternative Name: C5AR1 / CD88 / C5a Receptor

Background: Name/Gene ID: C5AR1
Subfamily: Anaphylatoxin
Family: GPCR

Synonyms: C5AR1, C5A, C5a-R, C5a ligand, C5a receptor, CD88, C5a anaphylatoxin receptor, C5AR, C5R1, CD88 antigen

Gene ID: 728

UniProt: P21730

Pathways: Complement System