C7 antibody (C-Term)

Catalog No. ABIN206670

This anti-C7 antibody is a Mouse Monoclonal antibody detecting C7 in WB, ELISA and Func. Suitable for Human.

Quick Overview for C7 antibody (C-Term) (ABIN206670)

Target: C7 (Complement Component C7 (C7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Functional Studies (Func)

Product Details anti-C7 Antibody

Binding Specificity: C-Term

Specificity: Recognizes complement component 7 (C7), a 110 kD glycoprotein present in the blood serum. The factor I domain of C7 binds the C terminus of the C5 alpha-chain, acting as a membrane anchor. This enables the assembly of the complement membrane attack complex (MAC) and consequent complement lytic activity. C7 deficiency is associated with increased susceptibility to recurrent infections, in particular by Neisseria meningitides. Note that Does not recognize membrane bound complement membrane attack complex. Inhibits lysis of sensitized sheep erythrocytes.

Purification: Protein A purified

Immunogen: Purified human C7.

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, Func, WB

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: BBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for C7

Target: C7 (Complement Component C7 (C7))

Alternative Name: Complement C7

Background: Name/Gene ID: C7
Subfamily: Complement Component

Synonyms: C7, Complement C7, Complement component 7, Complement component C7

Gene ID: 730

UniProt: P10643

Pathways: Complement System