C9 antibody

Catalog No. ABIN206672

The Mouse Monoclonal anti-C9 antibody has been validated for ELISA. It is suitable to detect C9 in samples from Human.

Quick Overview for C9 antibody (ABIN206672)

Target: C9 (Complement Component C9 (C9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C9 antibody is un-conjugated

Application: ELISA

Product Details anti-C9 Antibody

Specificity: Recognizes complement component 9 (C9), a 71kD member of the complement C6/C7/C8/C9 family present in the blood serum and synthesized by the liver and monocytes. C9 is the last component to be added during the formation of the membrane attack complex (MAC), binding the membrane associated C5b-8 complex and resulting in the circular polymerization of 12-18 C9 Molecules. This forms the hydrophilic transmembrane channel which causes cell lysis. Deficiency of C9 is associated with recurring infections by Neisseria meningitides. Does not recognize MAC.

Purification: Protein A purified

Immunogen: Purified human C9.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Borate buffered saline,  pH 8.2 - 8.4, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for C9

Target: C9 (Complement Component C9 (C9))

Alternative Name: Complement C9

Background: Name/Gene ID: C9
Subfamily: Complement Component

Synonyms: C9, Complement C9, Complement component 9, Complement component C9

Gene ID: 735

UniProt: P02748

Pathways: Complement System