ITGAL antibody

Catalog No. ABIN206891

The Mouse Monoclonal anti-ITGAL antibody has been validated for FACS, IP, Func, BR and Neut. It is suitable to detect ITGAL in samples from Human.

Quick Overview for ITGAL antibody (ABIN206891)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGAL antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Blocking Reagent (BR), Neutralization (Neut)

Clone: MEM-25

Product Details anti-ITGAL Antibody

Specificity: Reacts with CD11a (alpha-subunit of human LFA-1), a 170-180 kD type I transmembrane glycoprotein expressed on B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils.

Purification: Protein A purified

Immunogen: Leukocytes from a patient suffering from a LGL-type leukaemia.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Block, Flo, Func, IP, Neut

Usage: Flow Cytometry: Recommended dilution - 2 μg/mL. Immunoprecipitation: excellent antibody for immunoaffinity purification of LFA-1 complex. Functional Application: The antibody MEM-25 partially blocks binding of LFA-1 complex to ICAM-1. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Azide free PBS, preserved by filter sterilization, approx,  pH 7.4.

Preservative: Azide free

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Alternative Name: LFA-1 / CD11A

Background: Name/Gene ID: ITGAL
Family: Integrin

Synonyms: ITGAL, CD11A, Integrin alpha-L, LFA-1 alpha, LFA-1A, Integrin gene promoter, Alpha polypeptide), CD11a antigen, LFA-1, LFA1A

Gene ID: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex