CD42b antibody

Catalog No. ABIN207042

This anti-CD42b antibody is a Mouse Monoclonal antibody detecting CD42b in FACS, IHC, IHC (fro), Func and Inhibition. Suitable for Human and Primate.

Quick Overview for CD42b antibody (ABIN207042)

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Reactivity: Human, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD42b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Blocking Antibody (Inhibition)

Clone: HIP1

Product Details anti-CD42b Antibody

Specificity: Reacts with CD42b (GPIbalpha), a 135-145 kD membrane glycoprotein expressed on platelets and megakaryocytes. CD42b and CD42c (GPIbbeta) are composed in a disulfide linked heterodimer (CD42b/c, 160 kD), CD42b/c forms a noncovalent complex with CD42a and CD42d.

Purification: Protein G purified

Immunogen: Peripheral blood mononuclear cells of a patient suffering with CLL.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func, IHC, IHC-Fr, Inhb

Usage: Functional Application: The antibody HIP1 inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets and ristocetin-induced platelet agglutination.

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for CD42b

Target: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Alternative Name: GP1BA / CD42B

Background: Name/Gene ID: GP1BA

Synonyms: GP1BA, Antigen CD42b-alpha, CD42b antigen, BDPLT3, CD42b-alpha, DBPLT3, Glycoprotein Ibalpha, GPIbA, GP-Ib alpha, gp1B, GPIb-alpha, BDPLT1, BSS, CD42B, gp1BA, VWDP

Gene ID: 2811

UniProt: P07359