CD59 antibody
Quick Overview for CD59 antibody (ABIN208037)
Target
See all CD59 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Binds to a 17-25kD glycoprotein which is distributed on human cells and has a glycosyl-phosphatidylinositol (GPI) linkage to the plasma membrane. Cell reactivity: Recognizes all leucocytes, platelets, fibroblasts, erythrocytes and most cell lines. It is negative on U937 and Daudi cell lines. It is reduced on affected cells from patients with PNH with a distribution reflecting the clonal nature of the disease.
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Purification
- Purified
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Immunogen
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Human erythrocytes.
Type of Immunogen: Cells -
Isotype
- IgG1
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Application Notes
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Approved: ELISA, Flo (1:25), IF (1:25)
Usage: Suitable for use in Flow Cytometry, Indirect Immunofluorescence, and ELISA. Flow Cytometry: 1:25. Indirect Immunofluorescence: 1:25. Dilute with isotonic buffer. Use 50 μL of the appropriate dilution per 1x1 x106 in 100 μL buffer. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.2 M PBS, pH 7.4, 0.2 % BSA, 0.1 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
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Short term: -20°C
Long term: -20°C.
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- CD59
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Alternative Name
- CD59
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Background
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Name/Gene ID: CD59
Synonyms: CD59, 16.3A5, 1F5, 1F5 antigen, CD59 glycoprotein, EL32, EJ16, G344, HRF-20, MAC-IP, MACIF, Ly-6-like protein, MEM43, MIRL, MEM43 antigen, MIN2, MIN3, MSK21, p18-20, Protectin, MAC-inhibitory protein, MIC11, T cell-activating protein, CD59 antigen, EJ30, HRF20, Human leukocyte antigen MIC11, Lymphocytic antigen CD59/MEM43, MIN1 -
Gene ID
- 966
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UniProt
- P13987
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Pathways
- Complement System
Target
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