IL-6 Receptor antibody

Catalog No. ABIN208181

The Mouse Monoclonal anti-IL-6 Receptor antibody has been validated for IHC, IP, ELISA, FACS and IHC (fro). It is suitable to detect IL-6 Receptor in samples from Human.

Quick Overview for IL-6 Receptor antibody (ABIN208181)

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IL-6 Receptor Antibody

Specificity: Recognizes both the soluble and membrane bound human IL-6 receptor. B-R6 will inhibit IL-6 mediated proliferation of XG-1 cells and partially blocks the binding of IL-6 to its receptor.

Purification: Ion exchange chromatography

Immunogen: CHO cells transfected with cDNA of the human IL-6 receptor.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, Flo (1:50), IHC, IHC-Fr, IP

Usage: Suitable for use in Flow Cytometry, ELISA, Immunoprecipitation and Immunohistochemistry. Immunohistochemistry: Frozen tissues. Flow Cytometry: 1:50, Use 10 μL per 1 x10⁶ in 100 μL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: IL6R / IL6 Receptor

Background: Name/Gene ID: IL6R
Family: Interleukin

Synonyms: IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ

Gene ID: 3570

UniProt: P08887

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints