Muscarinic Acetylcholine Receptor M2 antibody (AA 225-359)

Catalog No. ABIN209066

The Rat Monoclonal anti-Muscarinic Acetylcholine Receptor M2 antibody has been validated for WB, IHC, IHC (p) and ICC. It is suitable to detect Muscarinic Acetylcholine Receptor M2 in samples from Human, Rat and Monkey.

Quick Overview for Muscarinic Acetylcholine Receptor M2 antibody (AA 225-359) (ABIN209066)

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Reactivity: Human, Rat, Monkey

Host: Rat

Clonality: Monoclonal

Conjugate: This Muscarinic Acetylcholine Receptor M2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-Muscarinic Acetylcholine Receptor M2 Antibody

Binding Specificity: AA 225-359

Specificity: M2 muscarinic acetylcholine receptor. No reactivity with the other subtypes. Species cross-reactivity: Human, monkey and rat. Expected to react with most mammalian species.

Purification: Purified

Immunogen: I3 loop of m2 receptor fusion protein (225-359), fused to Glutathione S-transferase.

Type of Immunogen: Fusion protein

Isotype: IgG2a

Application Details

Application Notes: Approved: ICC, IHC, IHC-P, WB

Usage: Suitable for use in Immunohistochemistry and Immunocytochemistry. Does not work on paraffin embedded tissues, and Western Blot. Immunohistochemistry (4 % paraformaldehyde fixed tissue): 1-5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for Muscarinic Acetylcholine Receptor M2

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Alternative Name: CHRM2 / M2

Background: Name/Gene ID: CHRM2
Subfamily: Acetylcholine
Family: GPCR

Synonyms: CHRM2, 7TM receptor, HM2, M2 muscarinic receptor, M2-mAChR, Muscarinic receptor M2, Muscarinic M2 receptor

Gene ID: 1129

UniProt: P08172