Muscarinic Acetylcholine Receptor M2 antibody (AA 3-20)

Catalog No. ABIN7139924

Product Details anti-Muscarinic Acetylcholine Receptor M2 Antibody

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Binding Specificity: AA 3-20

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Muscarinic Acetylcholine Receptor M2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Muscarinic acetylcholine receptor M2 protein (3-20AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Muscarinic Acetylcholine Receptor M2

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Alternative Name: CHRM2 (CHRM2 Products)

Synonyms: HM2 antibody, AChR-M2 antibody, Chrm-2 antibody, M2 antibody, chrm2 antibody, Acm2 antibody, GPM2 antibody, cholinergic receptor muscarinic 2 antibody, cholinergic receptor, muscarinic 2, cardiac antibody, cholinergic receptor, muscarinic 2a antibody, cholinergic receptor, muscarinic 2 antibody, CHRM2 antibody, Chrm2 antibody, chrm2a antibody

Background:

Background: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3), this then triggers calcium ion release into the cytosol.

Aliases: 7TM receptor antibody, Acetylcholine receptor, muscarinic, 2 antibody, AChR antibody, Acm2 antibody, ACM2_HUMAN antibody, Cholinergic receptor muscarinic 2 antibody, Cholinergic receptor, muscarinic 2, cardiac antibody, Cholinergic receptor, muscarinic 2, isoform a antibody, Cholinergic receptor, muscarinic 2a antibody, CHRM 2 antibody, CHRM2 antibody, chrm2a antibody, CM2 antibody, FLJ43243 antibody, HM 2 antibody, HM2 antibody, M2 antibody, M2 muscarinic receptor antibody, M2-mAChR antibody, MGC120006 antibody, MGC120007 antibody, Muscarinic acetylcholine receptor M2 antibody, Muscarinic M2 receptor antibody

UniProt: P08172