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CD13 antibody (AA 288-295)

ANPEP Reactivity: Human, Rhesus Monkey FACS, WB, IHC, ELISA, IHC (fro), IP Host: Mouse Monoclonal unconjugated
Catalog No. ABIN211563
  • Target See all CD13 (ANPEP) Antibodies
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    Binding Specificity
    • 16
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 288-295
    Reactivity
    • 140
    • 54
    • 22
    • 9
    • 7
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    Human, Rhesus Monkey
    Host
    • 91
    • 58
    • 16
    • 1
    • 1
    Mouse
    Clonality
    • 112
    • 52
    Monoclonal
    Conjugate
    • 70
    • 19
    • 17
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD13 antibody is un-conjugated
    Application
    • 109
    • 53
    • 36
    • 32
    • 31
    • 29
    • 19
    • 16
    • 16
    • 14
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
    Specificity
    Recognizes human CD13 also known as aminopeptidase N. CD13 is a single pass type II glycosylated integral membrane protein with a predicted molecular mass of ~110 kD and an apparent molecular mass of ~150 kD expressed by granulocytes, monocytes, fibroblasts, endothelial cells and by myeloid leukaemia cells. CD13 acts as a major cell surface receptor for group 1 coronoviruses which bind to a critical sequence encompassing amino acid residues 288-295. CD13 functions as an enzyme, a metalloprotease present as both a membrane bound form and also a soluble aminopeptidase N. Inhibits infection of cells by human coronavirus but not hepatitis C virus and inhibits aminopeptidase N activity of the CD13 Molecule.
    Purification
    Ion exchange chromatography
    Immunogen
    Human AML cells.

    Type of Immunogen: Cells
    Isotype
    IgG1
    Top Product
    Discover our top product ANPEP Primary Antibody
  • Application Notes
    Approved: ELISA, Flo, IHC, IHC-Fr, IP, WB

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target
    CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
    Alternative Name
    ANPEP / CD13 (ANPEP Products)
    Background
    Name/Gene ID: ANPEP
    Subfamily: Metallopeptidase M1
    Family: Exopeptidase

    Synonyms: ANPEP, Alanyl aminopeptidase, Aminopeptidase M, APN, Aminopeptidase N, AP-N, AP-M, CD13, CD13 antigen, HAPN, gp150, p150, PEPN, Microsomal aminopeptidase, LAP1
    Gene ID
    290
    UniProt
    P15144
    Pathways
    Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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