CD13 antibody (AA 288-295)
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- Target See all CD13 (ANPEP) Antibodies
- CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
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Binding Specificity
- AA 288-295
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Reactivity
- Human, Rhesus Monkey
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD13 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)
- Specificity
- Recognizes human CD13 also known as aminopeptidase N. CD13 is a single pass type II glycosylated integral membrane protein with a predicted molecular mass of ~110 kD and an apparent molecular mass of ~150 kD expressed by granulocytes, monocytes, fibroblasts, endothelial cells and by myeloid leukaemia cells. CD13 acts as a major cell surface receptor for group 1 coronoviruses which bind to a critical sequence encompassing amino acid residues 288-295. CD13 functions as an enzyme, a metalloprotease present as both a membrane bound form and also a soluble aminopeptidase N. Inhibits infection of cells by human coronavirus but not hepatitis C virus and inhibits aminopeptidase N activity of the CD13 Molecule.
- Purification
- Ion exchange chromatography
- Immunogen
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Human AML cells.
Type of Immunogen: Cells - Isotype
- IgG1
- Top Product
- Discover our top product ANPEP Primary Antibody
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- Application Notes
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Approved: ELISA, Flo, IHC, IHC-Fr, IP, WB
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
- Alternative Name
- ANPEP / CD13 (ANPEP Products)
- Background
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Name/Gene ID: ANPEP
Subfamily: Metallopeptidase M1
Family: Exopeptidase
Synonyms: ANPEP, Alanyl aminopeptidase, Aminopeptidase M, APN, Aminopeptidase N, AP-N, AP-M, CD13, CD13 antigen, HAPN, gp150, p150, PEPN, Microsomal aminopeptidase, LAP1 - Gene ID
- 290
- UniProt
- P15144
- Pathways
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
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