CD44 antibody

Catalog No. ABIN7470766

The Mouse Monoclonal anti-CD44 antibody has been validated for FACS, IHC, IHC (p) and IHC (fro). It is suitable to detect CD44 in samples from Human and Cynomolgus.

Quick Overview for CD44 antibody (ABIN7470766)

Target: CD44

Reactivity: Human, Cynomolgus

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD44 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: F10-44-2

Product Details anti-CD44 Antibody

Specificity: Recognizes the human CD44 cell surface antigen, a 100kD glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and of the breast. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. This product is routinely tested in flow cytometry on human peripheral blood lymphocytes.

Purification: Protein G purified

Immunogen: Human T lymphocytes.

Type of Immunogen: Cells

Isotype: IgG2a

Application Details

Application Notes: Approved: Flo (1:10 - 1:20), IHC, IHC-Fr, IHC-P (1:50 - 1:100)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for CD44

Target: CD44

Alternative Name: CD44

Background: Name/Gene ID: CD44

Synonyms: CD44, CDW44, CD44 antigen, Cell surface glycoprotein CD44, CSPG8, ECMR-III, Epican, HUTCH-I, LHR, MDU2, MC56, MIC4, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, PGP-I, Pgp1, Phagocytic glycoprotein I, MDU3, CD44R, HCELL, Heparan sulfate proteoglycan

Gene ID: 960

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling