Caveolin-1 antibody (N-Term)

Catalog No. ABIN213405

This anti-Caveolin-1 antibody is a Rabbit Polyclonal antibody detecting Caveolin-1 in IHC and IHC (p). Suitable for Human, Rat, Mouse, Dog, Pig, Cow, Rabbit, Sheep, Monkey, Horse, Guinea Pig and Bat.

Quick Overview for Caveolin-1 antibody (N-Term) (ABIN213405)

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Reactivity: Human, Rat, Mouse, Dog, Pig, Cow, Rabbit, Sheep, Monkey, Horse, Guinea Pig, Bat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caveolin-1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Caveolin-1 Antibody

Binding Specificity: N-Term

Brand: IHC-plus™

Specificity: Human CAV1 / Caveolin. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Galago, Marmoset, Mouse, Rat, Ferret, Sheep, Bovine, Dog, Cat, Bat, Horse, Rabbit, Pig, Guinea pig (100%) Elephant, Armadillo (93%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 15 amino acid peptide from N-terminus of human CAV1 / Caveolin. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Galago, Marmoset, Mouse, Rat, Ferret, Sheep, Bovine, Dog, Cat, Bat, Horse, Rabbit, Pig, Guinea pig (100%), Elephant, Armadillo (93%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Caveolin-1

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Alternative Name: CAV1 / Caveolin 1

Background: Name/Gene ID: CAV1

Synonyms: CAV1, Caveolin-1, CGL3, CAV, MSTP085, VIP21, BSCL3

Gene ID: 857

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals