PDE11A antibody (Internal Region)

Catalog No. ABIN213553

This Rabbit Polyclonal antibody specifically detects PDE11A in IHC and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Bat, Monkey, Pig, Chicken and Hamster.

Quick Overview for PDE11A antibody (Internal Region) (ABIN213553)

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Zebrafish (Danio rerio), Bat, Monkey, Pig, Chicken, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE11A antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PDE11A Antibody

Binding Specificity: Internal Region

Brand: IHC-plus™

Specificity: Human PDE11A. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PDE6B (53 % ).

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Bat, Hamster, Elephant, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Pufferfish, Zebrafish (100%) Platypus, Xenopus, Stickleback (94%) Dog (88%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 17 amino acid peptide from internal region of human PDE11A. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Bat, Hamster, Elephant, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Pufferfish, Zebrafish (100%), Platypus, Xenopus, Stickleback (94%), Dog (88%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PDE11A

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Alternative Name: PDE11A

Background: Name/Gene ID: PDE11A
Subfamily: PDE - cAMP/cGMP dual-specific
Family: Phosphodiesterase

Synonyms: PDE11A, Pde11, PDE11A4, PDE11A1, PPNAD2, PDE11A2, PDE11A3, Phosphodiesterase 11A

Gene ID: 50940

Pathways: cAMP Metabolic Process