BIRC2 antibody (C-Term)

Catalog No. ABIN214284

This anti-BIRC2 antibody is a Rabbit Polyclonal antibody detecting BIRC2 in WB, IHC, IF and IHC (p). Suitable for Human and Mouse.

Quick Overview for BIRC2 antibody (C-Term) (ABIN214284)

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BIRC2 Antibody

Binding Specificity: C-Term

Purification: Immunoaffinity purified

Isotype: IgG

Application Details

Application Notes: Approved: IF (20 μg/mL), IHC, IHC-P (2.5 μg/mL), WB (1 - 2 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 3 months and -20°C, stable for up to 1 year. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BIRC2

Target: BIRC2 (Baculoviral IAP Repeat Containing 2 (BIRC2))

Alternative Name: BIRC2 / cIAP1

Background: Name/Gene ID: BIRC2
Family: Apoptosis

Synonyms: BIRC2, API1, C-IAP1, CIAP1, Hiap-2, IAP homolog B, HIAP2, IAP-2, RNF48, Apoptosis inhibitor 1, IAP2, MIHB, RING finger protein 48

Gene ID: 329

UniProt: Q13490

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades