ESR2 antibody (AA 512-530)

Catalog No. ABIN215126

The Rabbit Polyclonal anti-ESR2 antibody has been validated for WB, IHC, IHC (p) and IHC (fro). It is suitable to detect ESR2 in samples from Mouse.

Quick Overview for ESR2 antibody (AA 512-530) (ABIN215126)

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ESR2 Antibody

Binding Specificity: AA 512-530

Specificity: Recognizes human and rat ER. Detects a band of ~55kD by Western blot. Does not cross-react with ER.

Predicted Reactivity: Percent identity by BLAST analysis: Mouse (100%) Human, Gorilla, Gibbon, Rat, Hamster (84%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to aa 512-530(C512CSTEDSKSKEGSQNLQSQ530) of C-terminal mouse ER (estrogen receptor ). Percent identity by BLAST analysis: Mouse (100%), Human, Gorilla, Gibbon, Rat, Hamster (84%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-Fr, IHC-P, WB (2 μg/mL)

Usage: Suitable for use in Immunohistochemistry and Western Blot. Immunohistochemistry (frozen and paraffin sections): 1-2 μg/mL. Western Blot: 2 μg/mL.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Epitope affinity purified IgG in PBS, 1 mg/mL BSA, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for ESR2

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Alternative Name: ESR2 / ER Beta

Background: Name/Gene ID: ESR2
Subfamily: NR3 Steroid receptor
Family: NHR

Synonyms: ESR2, ESTRB, ER Beta, ERbeta, ER-BETA, ESR-BETA, ESRB, Estrogen receptor 2 (ER beta), NR3A2, Estrogen receptor beta, Estrogen receptor beta 4

Gene ID: 2100

UniProt: Q92731

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling