DRD3 antibody (3rd Cytoplasmic Domain)

Catalog No. ABIN215786

The Rabbit Polyclonal anti-DRD3 antibody has been validated for WB and ELISA. It is suitable to detect DRD3 in samples from Rat and Mouse.

Quick Overview for DRD3 antibody (3rd Cytoplasmic Domain) (ABIN215786)

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRD3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DRD3 Antibody

Binding Specificity: 3rd Cytoplasmic Domain

Specificity: Specific for Dopamine Receptor D3. No significant sequence homology with other dopamine receptors (D1, D2, D4 or D5). Species sequence Homology: Mouse: 100 % , human/monkey: 63 %.

Purification: Affinity purified

Immunogen: Synthetic peptide 19aa sequence from the rat D3 receptor within the 3rd cytoplasmic domain.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.5 - 1 μg/mL), WB (1 - 10 μg/mL)

Usage: Suitable for use in Western Blot and ELISA. Western Blot: 1-10 μg/mL (ECL). Load ~100-400 μg of membrane protein/lane to visualize the receptor band. ELISA: 0.5-1 μg/mL (1 μg/mL immunogen peptide/well).

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 100 mM Tris,  pH 7.2, 0.2 % BSA, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for DRD3

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Alternative Name: DRD3 / Dopamine Receptor D3

Background: Name/Gene ID: DRD3
Subfamily: Dopamine
Family: GPCR

Synonyms: DRD3, D3 dopamine receptor, D3DR, Dopamine 3 receptor, Dopamine receptor D3, D3nf, Essential tremor 1, ETM1, FET1, D(3) dopamine receptor, Dopamine D3 receptor

Gene ID: 1814

UniProt: P35462

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity