DRD4 antibody (3rd Extracellular Domain)

Catalog No. ABIN215791

This Rabbit Polyclonal antibody specifically detects DRD4 in WB and ELISA. It exhibits reactivity toward Mouse.

Quick Overview for DRD4 antibody (3rd Extracellular Domain) (ABIN215791)

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRD4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DRD4 Antibody

Binding Specificity: 3rd Extracellular Domain

Specificity: Specific for Dopamine Receptor D4. Mouse Dopamine receptor D4 is a 387 aa, G-protein coupled and transmembrane receptor protein. The immunogen peptide shows no significant homology with other dopamine receptors (D1, D2, D3 or D5). Species Reactivity: the immunogen peptide shows sequence homology of 90 % with rat and human D4 receptors.

Purification: Affinity purified

Immunogen: A 10 amino acid peptide sequence from the mouse D4 receptor within the 3rd extracellular domain.

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.5 - 1 μg/mL), WB (1 - 10 μg/mL)

Usage: Western blot: 1-10 μg/mL (Chemiluminescence technique). Approximately 100-400 μg of membrane protein/lane should be loaded to visualize the receptor band. Immunohistochemistry: Has not been tested. It is recommended that the antibody be used at 1-20 μg/mL on paraformaldehyde fixed sections. ELISA: 0.5-1.0 μg/mL (1 μg/mL immunogen peptide/well).

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % BSA, 0.02 % sodium merthiolate.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for DRD4

Target: DRD4 (Dopamine Receptor D4 (DRD4))

Alternative Name: DRD4 / Dopamine Receptor D4

Background: Name/Gene ID: DRD4
Subfamily: Dopamine
Family: GPCR

Synonyms: DRD4, D(4) dopamine receptor, D4DR, D(2C) dopamine receptor, D4 dopamine receptor, Dopamine receptor D4, Dopamine 4 receptor, Dopamine D4 receptor

Gene ID: 1815

UniProt: P21917

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity