BTBD7 antibody (AA 41-130)

Catalog No. ABIN2170703

The Rabbit Polyclonal anti-BTBD7 antibody has been validated for ELISA, IHC (p), FACS, IF (cc), IF (p) and IHC (fro). It is suitable to detect BTBD7 in samples from Human and Rat.

Quick Overview for BTBD7 antibody (AA 41-130) (ABIN2170703)

Target: BTBD7 (BTB (POZ) Domain Containing 7 (BTBD7))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTBD7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-BTBD7 Antibody

Binding Specificity: AA 41-130

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BTBD7

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BTBD7

Target: BTBD7 (BTB (POZ) Domain Containing 7 (BTBD7))

Alternative Name: BTBD7

Background:

Synonyms: FUP1, BTB/POZ domain-containing protein 7, BTBD7, KIAA1525

Background: Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression (By similarity).

Gene ID: 55727

UniProt: Q9P203