C2ORF44 antibody (PE)

Catalog No. ABIN2171421

This anti-C2ORF44 antibody is a Rabbit Polyclonal antibody detecting C2ORF44 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for C2ORF44 antibody (PE) (ABIN2171421)

Target: C2ORF44 (Chromosome 2 Open Reading Frame 44 (C2ORF44))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C2ORF44 antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-C2ORF44 Antibody (PE)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C2orf44

Isotype: IgG

Application Details

Application Notes: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for C2ORF44

Target: C2ORF44 (Chromosome 2 Open Reading Frame 44 (C2ORF44))

Alternative Name: C2orf44

Background:

Synonyms: C2orf44, CB044_HUMAN, Chromosome 2 open reading frame 44, FLJ21945, PP384, WD repeat-containing protein C2orf44.

Background: The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The C2orf44 gene product has been provisionally designated C2orf44 pending further characterization.

Gene ID: 80304