CCDC11 antibody (AA 330-380) (AbBy Fluor® 647)

Catalog No. ABIN2172322

This Rabbit Polyclonal antibody specifically detects CCDC11 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for CCDC11 antibody (AA 330-380) (AbBy Fluor® 647) (ABIN2172322)

Target: CCDC11 (Coiled-Coil Domain Containing 11 (CCDC11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC11 antibody is conjugated to AbBy Fluor® 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CCDC11 Antibody (AbBy Fluor® 647)

Binding Specificity: AA 330-380

Specificity: Due to the similarity of this protein to RWD domain-containing protein 1, there is a chance that this antibody will react with this protein based on a 75 % non-sequential amino acid similarity.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CCDC11

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CCDC11

Target: CCDC11 (Coiled-Coil Domain Containing 11 (CCDC11))

Alternative Name: Ccdc11

Background:

Synonyms: HTX6, CCDC11, Coiled-coil domain-containing protein 11

Background: CCDC11 is a 514 amino acid protein encode by a gene that maps to human chromosome 18q21.1. Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGF modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18.

Gene ID: 220136

UniProt: Q96M91