LAG3 antibody

Catalog No. ABIN217397

The Rat Monoclonal anti-LAG3 antibody has been validated for FACS and Func. It is suitable to detect LAG3 in samples from Mouse.

Quick Overview for LAG3 antibody (ABIN217397)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This LAG3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: C9B7W

Product Details anti-LAG3 Antibody

Specificity: Recognizes murine lymphocyte activation gene-3 (LAG-3). Recognizes an epitope within the D2 domain of CD223. Reported to block the in vitro function of murine LAG-3, but studies suggest that the antibody does not block binding of LAG-3 to MHC class II.

Purification: Protein G purified

Immunogen: Murine CD223 Ig fusion protein.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:50 - 1:200), Func

Usage: Suitable for use in Flow Cytometry and Functional Assays. Flow Cytometry: 1:50-1:200. Use 10 μL to label 1 x10⁶ in 100 μL.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Alternative Name: LAG3 / LAG-3 / CD223

Background: Name/Gene ID: LAG3

Synonyms: LAG3, CD223 antigen, LAG-3, Protein FDC, CD223, FDC, Lymphocyte-activation gene 3

Gene ID: 3902

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints