MCC antibody (PE)

Catalog No. ABIN2177565

This anti-MCC antibody is a Rabbit Polyclonal antibody detecting MCC in WB. Suitable for Human, Mouse and Rat.

Quick Overview for MCC antibody (PE) (ABIN2177565)

Target: MCC (Mutated in Colorectal Cancers (MCC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCC antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-MCC Antibody (PE)

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MCC

Isotype: IgG

Application Details

Application Notes: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for MCC

Target: MCC (Mutated in Colorectal Cancers (MCC))

Alternative Name: Mcc

Background:

Synonyms: Colorectal mutant cancer protein, MCC 1, MCC-1, MCC1, Mutated in colorectal cancers, Protein MCC, CRCM_HUMAN.

Background: This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Gene ID: 4163

UniProt: P23508